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Table 2 Test parameters for patients with and without a diagnosis of CAN

From: Heart rate variability tests for diagnosing cardiovascular autonomic neuropathy in patients with type 2 diabetes mellitus in advanced stages of kidney disease

Variables

Without CAN

With CAN

p

N = 12

n = 36

Frequency domain parameters

TP (ms2)

2733 (536-3178.5)

359.5 (111–1278)

0.007

VLF (ms2)

522 (212–1925)

212 (75.5-499.5)

0.024

LF (ms2)

332 (96-1091)

57 (22.5–182)

0.025

HF (ms2)

415.5 (72-1298)

72(15-451.5)

0.086

LF/HF (ms2)

1.12 (0.37–2.35)

0.63 (0.36–1.3)

0.617

Time domain parameters

RRmin (ms)

685 ± 272

708 ± 185

0.909

RRmax (ms)

1125 (906–1224)

935 (758–1070)

0.287

RRNN (ms)

935 ± 226

832 ± 244

0.122

SDNN (ms)

48 (24–60)

20 (11–34)

0.012

Autonomic cardiac reactivity tests

Deep breathing

1.13 (1.09–1.20)

1.06 (1.03–1.06)

0.027

Orthostatism test (30:15)

1.08 (1.05–1.75)

1.04 (1.02–1.06)

0.003

Valsalva Maneuver

1.43 (1.22–1.65)

1.18 (1.14–1.28)

0.006

  1. CAN = Cardiovascular autonomic neuropathy. TP = Total power. VLF = Very low frequency. LF = Low frequency. HF = High frequency. RRmin = Shorter RR Interval. RRmax = Longest RR. Interval. RRNN = mean value of normal RR intervals. SDNN = Standard deviation of normal RR intervals.
  2. Source: Author data.