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Table 4 Associations between obesity and incident CVD in CHARLS

From: How does biological age acceleration mediate the associations of obesity with cardiovascular disease? Evidence from international multi-cohort studies

Outcome

Obesity

Association, OR (95% CICI)

Per SD

Tertile 1

Tertile 2

Tertile 3

Ptrend

Stroke

 

BMI

1.27 (1.12–1.43)

Ref

1.30 (0.93–1.82)

1.78 (1.12–2.76)

0.01

 

WC

1.32 (1.13–1.53)

Ref

1.20 (0.74–1.91)

1.99 (1.39–2.88)

 < 0.01

 

WtHR

1.36 (1.17—1.58)

Ref

1.62 (1.07–2.48)

2.36 (1.56–3.63)

 < 0.01

 

BRI

1.32 (1.15–1.52)

Ref

1.62 (1.07–2.48)

2.36 (1.56–3.63)

 < 0.01

 

CVAI

1.42 (1.21–1.66)

Ref

1.36 (0.89–2.09)

2.00 (1.31–3.08)

 < 0.01

 

LAP

1.14 (1.01–1.28)

Ref

2.01 (1.32–3.08)

2.29 (1.43–3.70)

 < 0.01

 

TyG

1.25 (1.06–1.48)

Ref

1.15 (0.78–1.69)

1.25 (0.81–1.95)

0.33

 

TyG-BMI

1.35 (1.18–1.55)

Ref

2.14 (1.42–3.29)

2.48 (1.59–3.94)

 < 0.01

 

TyG-WC

1.41 (1.20–1.66)

Ref

1.65 (1.08–2.54)

2.50 (1.62–3.91)

 < 0.01

 

TyG-WtHR

1.48 (1.25–1.74)

Ref

1.73 (1.15–2.65)

2.10 (1.34–3.32)

 < 0.01

Heart disease

 

BMI

1.17 (1.06–1.29)

Ref

1.28 (1.01–1.62)

1.61 (1.16–2.21)

 < 0.01

 

WC

1.23 (1.10–1.37)

Ref

1.39 (1.03–1.87)

1.48 (1.15–1.91)

 < 0.01

 

WtHR

1.18 (1.06–1.32)

Ref

1.08 (0.83–1.42)

1.23 (0.93–1.63)

0.14

 

BRI

1.19 (1.07–1.32)

Ref

1.08 (0.83–1.42)

1.23 (0.93–1.63)

0.14

 

CVAI

1.21 (1.08–1.36)

Ref

1.25 (0.95–1.65)

1.50 (1.12–2.02)

0.01

 

LAP

1.01 (0.90–1.12)

Ref

1.37 (1.05–1.81)

1.39 (1.01–1.91)

0.05

 

TyG

1.02 (0.90–1.16)

Ref

1.16 (0.89–1.50)

1.01 (0.74–1.39)

0.86

 

TyG-BMI

1.17 (1.05–1.30)

Ref

1.19 (0.91–1.56)

1.42 (1.06–1.91)

0.02

 

TyG-WC

1.21 (1.07–1.36)

Ref

1.27 (0.97–1.67)

1.54 (1.15–2.07)

 < 0.01

 

TyG-WtHR

1.17 (1.04–1.33)

Ref

1.18 (0.89–1.56)

1.49 (1.11–2.02)

0.01

CVD

 

BMI

1.22 (1.12–1.33)

Ref

1.31 (1.06–1.61)

1.75 (1.31–2.31)

 < 0.01

 

WC

1.30 (1.18–1.42)

Ref

1.38 (1.05–1.80)

1.76 (1.41–2.20)

 < 0.01

 

WtHR

1.25 (1.14–1.38)

Ref

1.23 (0.97–1.56)

1.56 (1.22–1.99)

 < 0.01

 

BRI

1.25 (1.14–1.37)

Ref

1.23 (0.97–1.56)

1.56 (1.22–1.99)

 < 0.01

 

CVAI

1.30 (1.17–1.44)

Ref

1.25 (0.98–1.60)

1.73 (1.34–2.24)

 < 0.01

 

LAP

1.10 (1.01–1.20)

Ref

1.54 (1.21–1.97)

1.70 (1.29–2.25)

 < 0.01

 

TyG

1.11 (1.00–1.24)

Ref

1.17 (0.93–1.47)

1.12 (0.85–1.47)

0.39

 

TyG-BMI

1.26 (1.14–1.38)

Ref

1.49 (1.18–1.90)

1.79 (1.38–2.33)

 < 0.01

 

TyG-WC

1.32 (1.19–1.47)

Ref

1.38 (1.08–1.76)

1.93 (1.49–2.50)

 < 0.01

 

TyG-WtHR

1.29 (1.16–1.44)

Ref

1.35 (1.06–1.72)

1.71 (1.31–2.23)

 < 0.01

  1. Bold text in the table represents statistically significant results
  2. Models adjusted for age, sex, education level, marital status, residential area, smoking pack years, alcohol use, hypertension, diabetes, and hyperlipidemia.
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Cardiovascular Diabetology

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