Skip to main content

Table 1 Baseline characteristics according to TyG control level classes.

From: Association between cumulative changes of the triglyceride glucose index and incidence of stroke in a population with cardiovascular-kidney-metabolic syndrome stage 0–3: a nationwide prospective cohort study

 

Overall (N = 4700)

Class 1 (N = 1884)

Class 2 (N = 1093)

Class 3 (N = 1106)

Class 4 (N = 617)

P value

Age, n (%)

     

0.008

 < 60

2827 (60.1)

1092 (58.0)

682 (62.4)

654 (59.1)

399 (64.7)

 

 ≥ 60

1873 (39.9)

792 (42.0)

411 (37.6)

452 (40.9)

218 (35.3)

 

Gender, n (%)

     

< 0.001

 Female

2596 (55.2)

922 (48.9)

665 (60.8)

636 (57.5)

373 (60.5)

 

 Male

2104 (44.8)

962 (51.1)

428 (39.2)

470 (42.5)

244 (39.5)

 

BMI, kg/m2 (mean (SD))

23.65 (7.69)

22.37 (3.69)

24.68 (14.26)

23.75 (3.65)

25.54 (3.80)

< 0.001

Education, n (%)

     

0.870

 Lower than high school

4278 (91.0)

1711 (90.8)

993 (90.9)

1007 (91.0)

567 (91.9)

 

 High school or above

422 (9.0)

173 (9.2)

100 (9.1)

99 (9.0)

50 (8.1)

 

Smoking status, n (%)

     

0.001

 Non-smokers

2947 (62.7)

1117 (59.3)

711 (65.1)

705 (63.7)

414 (67.1)

 

 Smokers

1753 (37.3)

767 (40.7)

382 (34.9)

401 (36.3)

203 (32.9)

 

Drinking status, n (%)

     

0.082

 Never

2897 (61.7)

1121 (59.6)

698 (63.9)

696 (63.0)

382 (61.9)

 

 Ever

1799 (38.3)

761 (40.4)

394 (36.1)

409 (37.0)

235 (38.1)

 

CKM syndrome stages, n (%)

     

< 0.001

 0

199 (4.2)

162 (8.6)

28 (2.6)

9 (0.8)

0 (0.0)

 

 1

578 (12.3)

355 (18.8)

166 (15.2)

57 (5.2)

0 (0.0)

 

 2

1390 (29.6)

362 (19.2)

361 (33.0)

445 (40.2)

222 (36.0)

 

 3

2533 (53.9)

1005 (53.3)

538 (49.2)

595 (53.8)

395 (64.0)

 

Hypertension, n (%)

     

< 0.001

 No

2026 (61.9)

890 (70.2)

452 (59.7)

466 (59.4)

218 (47.2)

 

 Yes

1246 (38.1)

378 (29.8)

305 (40.3)

319 (40.6)

244 (52.8)

 

Diabetes, n (%)

     

< 0.001

 No

3962 (84.3)

1774 (94.2)

983 (89.9)

884 (79.9)

321 (52.0)

 

 Yes

738 (15.7)

110 (5.8)

110 (10.1)

222 (20.1)

296 (48.0)

 

Dyslipidemia,n (%)

     

< 0.001

 No

4263 (91.9)

1774 (95.2)

976 (90.4)

1002 (92.4)

511 (83.8)

 

 Yes

375 (8.1)

89 (4.8)

104 (9.6)

83 (7.6)

99 (16.2)

 

Antidiabetic agents, n (%)

     

< 0.001

 No

4552 (97.0)

1864 (98.9)

1068 (97.8)

1075 (97.5)

545 (88.5)

 

 Yes

143 (3.0)

20 (1.1)

24 (2.2)

28 (2.5)

71 (11.5)

 

Antihyperlipidemic agents, n (%)

     

< 0.001

 No

4457 (96.1)

1823 (97.9)

1037 (96.0)

1046 (96.5)

551 (90.3)

 

 Yes

180 (3.9)

40 (2.1)

43 (4.0)

38 (3.5)

59 (9.7)

 

Antihypertension agents, n (%)

     

< 0.001

 No

4021 (85.7)

1705 (90.6)

917 (84.0)

939 (85.0)

460 (74.8)

 

 Yes

673 (14.3)

177 (9.4)

175 (16.0)

166 (15.0)

155 (25.2)

 

TG, mg/dl (mean (SD))

132.80 (108.05)

74.16 (21.56)

110.03 (34.27)

162.65 (62.50)

298.66 (194.81)

< 0.001

Glucose, mg/dl (mean (SD))

109.44 (35.48)

98.35 (14.77)

102.96 (16.06)

112.68 (26.92)

148.93 (71.74)

< 0.001

HbA1c, % (mean (SD))

5.25 (0.79)

5.09 (0.46)

5.20 (0.55)

5.23 (0.66)

5.89 (1.50)

< 0.001

Hemoglobin, g/dl (mean (SD))

14.35 (2.20)

14.21 (2.22)

14.32 (2.15)

14.46 (2.23)

14.61 (2.12)

< 0.001

LDL-cholesterol, mg/dl (mean (SD))

115.91 (34.44)

111.23 (29.43)

126.04 (33.63)

118.14 (35.62)

108.21 (42.54)

< 0.001

HDL-cholesterol, mg/dl (mean (SD))

51.21 (15.23)

57.88 (15.02)

51.20 (13.25)

47.51 (13.02)

37.50 (10.72)

< 0.001

TC, mg/dl (mean (SD))

193.13 (37.92)

181.89 (33.29)

197.81 (36.87)

197.88 (37.70)

210.62 (43.04)

< 0.001

Uric acid, mg/dl (mean (SD))

4.34 (1.21)

4.18 (1.14)

4.34 (1.13)

4.43 (1.25)

4.66 (1.38)

< 0.001

eGFR, mL/min/1.73 m2 (mean (SD))

93.98 (13.90)

95.05 (13.18)

93.82 (14.27)

92.69 (13.99)

93.32 (14.92)

< 0.001

TyG2012 (mean (SD))

8.68 (0.67)

8.15 (0.31)

8.58 (0.33)

9.04 (0.34)

9.79 (0.59)

< 0.001

TyG2015 (mean (SD))

8.71 (0.63)

8.21 (0.31)

9.17 (0.34)

8.57 (0.29)

9.71 (0.48)

< 0.001

Cumulative TyG (mean (SD))

26.08 (1.73)

24.53 (0.68)

26.62 (0.76)

26.41 (0.71)

29.26 (1.16)

< 0.001

Outcome

 Incidence of stroke

280 (6.0)

92 (4.9)

74 (6.8)

70 (6.3)

44 (7.1)

0.073

Back to article page

Cardiovascular Diabetology

ISSN: 1475-2840