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Fig. 1 | Cardiovascular Diabetology

Fig. 1

From: Extracellular vesicle-associated miR-515-5p from adipose tissue regulates placental metabolism and fetal growth in gestational diabetes mellitus

Fig. 1

Characterization of miRNA enrichment adipose tissue and EVs in normal and gestational diabetes pregnancy. Volcano plot of miRNA expression in (A) NGT adipose compared to GDM adipose, (B) NGT EVs compared to GDM EVs, (C) NGT adipose compared to NGT EVs, and (D) GDM adipose compared to GDM EVs. (E) Comparative analysis of miR-146a-5p, miR-515-5p and miR-516-5p in (a-c) adipose tissue, (d-f) EVs and (g-i) placenta from NGT and GDM pregnancy (n = 8–12/ sample/condition). The fold change was calculated relative to NGT tissues. Non-parametric Mann–Whitney U test was performed. Data presented as mean ± SEM. *p< 0.05

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Cardiovascular Diabetology

ISSN: 1475-2840