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Table 1 Incidence rates and HRs of incident CVD events according to CKM stages or CVH status

From: Life’s Essential 8 cardiovascular health, cardiovascular-kidney-metabolic syndrome stages, and incident cardiovascular events: a nationwide 10-year prospective cohort study in China

 

No. of events/no. of participants

Person-years

Incidence rate, per 1000 person-years

Unadjusted HR (95% CI)

Adjusted HR (95% CI) a

CKM stage

Stage 0

83/4168

41427.1

2.0

1.00

1.00

Stage 1

626/21,540

214302.1

2.9

1.45 (1.16–1.83)

1.20 (0.95–1.51)

Stage 2

4197/61,894

601133.9

7.0

3.47 (2.80–4.32)

2.45 (1.97–3.04)

Stage 3

1552/6598

56464.3

27.5

13.26 (10.63–16.53)

4.43 (3.53–5.58)

Stage 4

1433/6527

57663.7

24.9

12.38 (9.93–15.45)

5.95 (4.75–7.45)

CVH status

 Overall CVH

  Low

2580/18,129

167206.0

15.4

1.00

1.00

  Moderate

5161/76,114

738720.6

7.0

0.45 (0.43–0.47)

0.56 (0.53–0.59)

  High (Optimal)

150/6484

65064.5

2.3

0.15 (0.13–0.18)

0.27 (0.23–0.32)

 Health behavior

  Low

2344/24,431

232014.5

10.1

1.00

1.00

  Moderate

4860/64,349

621705.0

7.8

0.78 (0.74–0.82)

0.87 (0.83–0.92)

  High (Optimal)

687/11,947

117271.6

5.9

0.59 (0.54–0.64)

0.75 (0.69–0.82)

 Health factor

  Low

3173/22,831

211398.2

15.0

1.00

1.00

  Moderate

4133/56,869

549899.5

7.5

0.50 (0.47–0.52)

0.59 (0.56–0.62)

  High (Optimal)

585/21,027

209693.4

2.8

0.18 (0.17–0.20)

0.31 (0.28–0.34)

  1. CVD cardiovascular disease; CKM cardiovascular-kidney-metabolic; CVH cardiovascular health; HR hazard ratio; CI confidence interval
  2. a HRs according to CKM stage or overall CVH status were adjusted for age, sex, and educational attainment (< 9 years vs. ≥ 9 years). For the analysis health behavior or health factor, other metrics of CVH were mutually adjusted