Fig. 1
From: Impaired cardiac branched-chain amino acid metabolism in a novel model of diabetic cardiomyopathy
A-PDK1KO mice exhibited impaired glucose utilization in the heart. A Plasma glucose concentrations of control mice and A-PDK1KO mice (n = 10, each group). B–D Body weights B, lean mass C, and fat mass D of 14-week-old mice were measured (n = 7, each group). E Representative images of Western blots of heart tissue and quantification of the band intensity in mice intraperitoneally injected with 0.9% saline or 5 U/kg insulin after a 4-hour fast (n = 8, each group). The data are shown as means ± SEs. Significance was calculated by the unpaired Student’s t test. *p value < 0.05, **p value < 0.01, ***p value < 0.001, and ****p value < 0.0001. BW, body weight; Ctrl, control mice; KO, A-PDK1KO mice