Joint association of triglyceride glucose index (TyG) and body roundness index (BRI) with stroke incidence: a national cohort study

Table 2 Association of TyG and BRI and the risk of stroke incidence

	Case	Incidence rate^a (95% CI)	Crude model		Model 1		Model 2		Model 3
	Case	Incidence rate^a (95% CI)	HR (95% CI)	P value	HR (95% CI)	P value	HR (95% CI)	P value	HR (95% CI)	P value
TyG
Low TyG	289	9.9 (8.8–11.1)	Ref		Ref		Ref		Ref
High TyG	454	15.8 (14.4–17.3)	1.62 (1.40–1.87)	< 0.001	1.66 (1.43–1.92)	< 0.001	1.52 (1.30–1.76)	< 0.001	1.25 (1.05–1.49)	0.015
BRI
Low BRI	270	9.2 (8.2–10.4)	Ref		Ref		Ref		Ref
High BRI	473	16.5 (15.1–18.0)	1.82 (1.56–2.11)	< 0.001	1.92 (1.64–2.24)	< 0.001	1.71 (1.46–2.00)	< 0.001	1.46 (1.24–1.73)	< 0.001
TyG and BRI
Low TyG and low BRI	141	7.7 (6.5–9.1)	Ref		Ref		Ref		Ref
High TyG and low BRI	129	11.9 (10.0–14.2)	1.57 (1.24–2.00)	< 0.001	1.64 (1.29–2.09)	< 0.001	1.56 (1.23–1.98)	< 0.001	1.36 (1.05–1.75)	0.019
Low TyG and high BRI	148	13.7 (11.7–16.2)	1.82 (1.45–2.29)	< 0.001	1.95 (1.54–2.47)	< 0.001	1.78 (1.40–2.25)	< 0.001	1.61 (1.27–2.05)	< 0.001
High TyG and high BRI	325	18.1 (16.3–20.2)	2.43 (1.99–2.96)	< 0.001	2.62 (2.14–3.21)	< 0.001	2.26 (1.84–2.79)	< 0.001	1.78 (1.40–2.26)	< 0.001

^a Per 1000 person-years
Model 1: adjusted for age and sex
Model 2: adjusted for variables in Model 1 plus smoking, drinking, marital status, education level, residence, and SBP
Model 3: adjusted for variables in Model 2 plus heart disease, diabetes, hypertension, hyperlipidemia, kidney disease, C-reactive protein, and uric acid
Abbreviations: BRI: body roundness index; TyG: triglyceride glucose

ISSN: 1475-2840