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Table 3 LLACS according to FibroTest® categories

From: Metabolic dysfunction-associated steatotic liver disease (MASLD) biomarkers and progression of lower limb arterial calcification in patients with type 2 diabetes: a prospective cohort study

Characteristic

Total

FibroTest® stages

p value for trend

F0

F1

F2

F3-F4

All patients

Participants, n (%)

150

59 (39%)

41 (27%)

21 (14%)

29 (19%)

 

LLACS at baseline, AU

503 [44 to 2224]

181 [0 to 1449]

434 [102 to 2311]

923 [349 to 2196]

1199 [287 to 3998]

0.050

LLACS at the end of follow-up, AU

1242 [132 to 4112]

421 [20 to 3382]

1298 [95 to 4169]

1462 [609 to 3275]

2707 [845 to 7400]

0.042

Absolute change in LLACS, AU

547 [53 to 1761]

243 [14 to 881]

685 [49 to 2037]

644 [311 to 1650]

1424 [427 to 3858]

0.030

Annualized change in LLACS, AU/year

215 [21 to 688]

90 [5.4 to 382]

291 [19 to 781]

248 [125 to 633]

465 [140 to 1674]

0.023

Patients with no progression of LLACS

Participants, n (%)

23

13 (57%)

8 (35%)

0 (0%)

2 (9%)

0.037

  1. Data are presented as median [1st to 3rd quartiles] or number (percentage), as appropriate. Individuals with F3 or F4 stages were grouped together to reach a significant number of subjects. P-values in bold indicate statistical significance. AU, Agatston unit; LLACS, lower limb arterial calcification score