Fig. 2

Boxplots of the scaled and centred log-transformed intensity of each lipid significantly associated with the presence of SCA in smokers with T2D and in individuals with T2D without dyslipidaemia. All lipids shown correspond to LC–MS features acquired in positive ionization mode. The first 14 plots correspond to the smoking habit comparison, while the last 2 represent the dyslipidaemia comparison. Each plot title displays the lipid name and the number of observations. The x-axis labels indicate the sub-group of individuals analysed. The q-values for each comparison are displayed at the top of the plots. CE, cholesterol esters; Cer, ceramides; LPC, lysophosphatidylcholine; LPE, lysophosphatidylethanolamine; PC, phosphatidylcholine; PE, phosphatidylethanolamine; TG, triacylglycerols. Mix indicates an LC–MS feature that includes multiple lipid species with the same sum composition notation