Table 4 Associated factors of biventricular indexed EAT volume in multivariable linear regression analysis in HFpEF patients in the Belgian cohort

Age (years)

− 0.26

− 0.78, 0.27

Diabetes

14

6.80, 22

0.15, 16.49

Female

− 1.8

− 10.0, 6.40

BMI (kg/m²)

0.75

0.15, 1.40

Metabolic syndrome

13

− 0.43, 26

Atrial fibrillation history

0.33

− 7.90, 8.60

Ischemic cardiomyopathy history

13

5.20, 21

2.58, 18.94

Hypercholesterolemia

3.70

− 5.10, 13

Ejection fraction, Simpson (%), by echo

− 0.22

− 0.79, 0.34

LV global longitudinal strain (%)

1.40

0.13, 2.70

-0.38, 2.11

RV fractional area change

− 6.90

− 55, − 41

E/e' ratio

0.70

0.13, 1.30

Left ventricle mass, indexed, by CMR (g/m²)

0.20

− 0.07, 0.46

LGE (%)

1.20

− 0.34, 2.70

eGFR by CK-EPI (ml/min/1.73m²)

− 0.12

− 0.32, 0.09

Blood glucose (mg/dL)

0.05

− 0.02, 0.12

Glycated hemoglobin (log %)*

− 0.72

− 5.40, 4

Triglycerides (mg/dL)

0.01

− 0.08, 0.11

CRP (log mg/dL)

1.10

− 5.40, 7.60

Neutrophils (log 10³/µL)

23

0.75, 46

hsTnT (log pg/mL)

12

− 1.50, 26

NT-proBNP (log pg/mL)

1.10

− 8.10, 10

FGF-23 (log RU/mL)

− 0.94

− 9.80, 7.90

ST2 soluble (log ng/mL)

16

− 2.70, 35

2.39,39.97

Mean platelet volume (fL)

− 3.40

− 7.70, 0.80

Insulin*

− 1.9

− 15, 12

Gliptin*

− 1.8

− 25, 22

Metformin*

− 3.3

− 21, 14