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Table 2 Baseline characteristics of controls, pre-HF patients, and HFpEF patients in the Belgian and the Beta3-LVH cohorts

From: Exploring the impact of metabolic comorbidities on epicardial adipose tissue in heart failure with preserved ejection fraction

 

Belgian cohort

Beta3-LVH cohort

Belgian cohort

Belgian cohort

 

Controls

Pre-HF

Pre-HF

HFpEF

 

N = 26

N = 191

N = 16

N = 104

Age (years)

76 ± 5

64 ± 10

75 ± 4

77 ± 8

Female (n, %)

17 (65.4%)

53 (27.7%)

10 (62.5%)

58 (55.8%)

BMI (kg/m2)

25.5 ± 3.3

29.8 ± 4.41

27.2 ± 4.2

28.9 ± 6.6

Diabetes (n, %)

3 (11.5%)

37 (19.4%)

4 (26.7%)

44 (42.3%)

Atrial fibrillation (n, %)

1 (3.9%)

3 (1.6%)

3 (18.8%)

62 (59.6%)

eGFR (mL/min/1.73m2) by CK-EPI

71.0 [54.5–80.8]

78.2 [69.9–91.0]

57.0 [49.5–68.5]

55.0 [40.8–67.0]

LA volume indexed (ml/m2) by Echo

19.0 ± 5.9

34.0 ± 11.0

30.7 ± 10.4

44.2 ± 19.1

LV ejection Fraction (%) by Echo

64.9 ± 5.3

63.0 ± 6.0

66.6 ± 5.6

62.6 ± 7.2

LV mass indexed (g/m2) by CMR

59.1 ± 12.1

58.0 ± 7.0

58.8 ± 12.1

67.7 ± 15.4

E/e’ ratio

9.7 ± 1.8

9.3 ± 3.1

17.1 ± 5.4

17.7 ± 6.9

H2FPEF Score

2.2 ± 1.0

3.1 ± 1.4

4.3 ± 1.4

6.0 ± 1.8

Indexed EAT volume (ml/m2)

48.0 ± 8.9

52.0 ± 15.0

55.0 ± 11.8

72.4 ± 20.8

  1. BMI Body mass index, CMR Cardiac magnetic resonance, EAT Epicardial adipose tissue, eGFR Estimated glomerular filtration rate, HF Heart failure, HFpEF Heart failure with preserved ejection fraction, LV Left ventricular