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Table 3 Subgroup analysis of the association between AIP index trajectories and incident of CVD

From: Association of atherogenic index of plasma trajectory with the incidence of cardiovascular disease over a 12-year follow-up: findings from the ELSA cohort study

Variable

HR (95% CI)

P for trend

P for interaction

Low stable

Moderate stable

High stable

Age

    

0.001

< 63

Ref

1.47(1.00, 2.14)

2.04(1.30, 3.19)

0.002

 

≥ 63

Ref

1.1(0.86, 1.41)

1.04(0.74, 1.46)

0.712

 

Gender

    

0.099

Female

Ref

1.3(0.98, 1.71)

1.17(0.78, 1.75)

0.237

 

Male

Ref

1.08(0.79, 1.48)

1.42(0.99, 2.04)

0.056

 

WWI

    

0.109

≥ 10.9

Ref

1.33(0.97, 1.81)

1.25(0.87, 1.80)

0.273

 

< 10.9

Ref

1.06(0.80, 1.41)

1.62(1.08, 2.42)

0.055

 

Drinking status

    

0.237

Never

Ref

0.94(0.48, 1.84)

0.88(0.38, 2.07)

0.778

 

Ever

Ref

1.23(0.99, 1.52)

1.4(1.06, 1.85)

0.015

 

Alcohol consumption

    

0.002

0

Ref

1.11(0.76, 1.63)

0.88(0.54, 1.45)

0.655

 

1

Ref

1.46(0.72, 2.98)

1.38(0.54, 3.54)

0.430

 

2

Ref

0.98(0.57, 1.68)

0.88(0.35, 2.19)

0.806

 

> 2

Ref

1.72(0.96, 3.06)

2.83(1.37, 5.86)

0.005

 

Physical activity

    

0.681

Low

Ref

1.16(0.76, 1.78)

1.22(0.73, 2.05)

0.458

 

Moderate

Ref

1.17(0.88, 1.55)

1.41(0.98, 2.04)

0.069

 

High

Ref

1.20(0.77, 1.86)

1.14(0.63, 2.07)

0.566

 

CVD in baseline

    

0.343

No

Ref

1.16(0.94, 1.44)

1.3(0.99, 1.70)

0.058

 

Yes

Ref

2.07(0.73, 5.81)

1.81(0.50, 6.62)

0.357

 
  1. The Model was adjusted for age, gender, WWI, education, smoking status, drinking status, diabetes, hypertension, CVD in baseline, Total cholesterol and LDL-C. HR, hazard ratio; CI, confidence interval; AIP, atherogenic index of plasma; WWI, weight-adjusted waist index; CVD, cardiovascular disease; LDL-C, low density lipoprotein cholesterol. Bold values represent significant p values