Table 2 Baseline characteristics among MASLD individuals with prediabetes or diabetes by mortality status
Variables | Alive N = 994 | Deceased N = 1163 | p |
|---|---|---|---|
Age, years | 44.0 (36.0, 51.0) | 62.0 (53.0, 68.0) | < 0.001 |
Men, n (%) | 452 (51.3) | 574 (50.6) | 0.837 |
Ethnicity, n (%) |  |  | < 0.001 |
 Non-Hispanic White | 254 (66.9) | 531 (83.9) |  |
 Non-Hispanic Black | 252 (11.4) | 243 (8.4) |  |
 Mexican American | 440 (10.2) | 364 (4.5) |  |
 Other ethnicities | 48 (11.6) | 25 (3.1) |  |
Family income ratio, n (%) | Â | Â | 0.992 |
 < 1.3 | 327 (16.6) | 344 (16.9) |  |
 1.3–3.5 | 487 (51.0) | 595 (50.9) |  |
 > 3.5 | 180 (32.4) | 224 (32.2) |  |
Married, n (%) | 736 (78.7) | 781(71.1) | 0.042 |
Education level, n (%) |  |  | < 0.001 |
 <=12 | 726 (59.8) | 934 (72.3) |  |
 > 12 | 268 (40.2) | 229 (27.7) |  |
Current smoker, n (%) | 172 (19.3) | 247 (21.6) | 0.504 |
SBP, mmHg | 123.0 (113.0, 132.0) | 134.0 (124.0, 148.0) | < 0.001 |
DBP, mmHg | 78.0 (72.0, 85.0) | 77.0 (71.0, 84.0) | 0.345 |
BMI, kg/m2 | 29.8 (26.5, 34.4) | 29.8 (26.4, 33.7) | 0.794 |
WC, cm | 102.2 (93.0, 110.5) | 104.5 (97.0, 113.0) | 0.001 |
FBG, mmol/L | 5.7 (5.2, 6.2) | 5.7 (5.2, 6.9) | 0.079 |
HbA1c, % | 5.6 (5.2, 5.9) | 5.8 (5.4, 6.3) | < 0.001 |
TG, mmol/L | 1.8 (1.2, 2.7) | 2.0 (1.4, 2.9) | 0.006 |
HDL-C, mmol/L | 1.1 (0.9, 1.3) | 1.1 (0.9, 1.3) | 0.404 |
Creatinine, umol/L | 97.2 (79.6, 106.1) | 97.2 (88.4, 106.1) | 0.002 |
PLT, 109/L | 269.5 (228.9, 320.2) | 261.5 (214.5, 307.5) | 0.009 |
ALT, U/L | 21.0 (15.0, 29.0) | 17.0 (12.0, 23.0) | < 0.001 |
AST, U/L | 21.0 (18.0, 26.0) | 20.0 (17.0, 25.0) | 0.056 |
FIB-4 > 1.3, n (%) | 116 (8.3) | 480 (41.6) | < 0.001 |
TyG index | 9.0 (8.6, 9.6) | 9.2 (8.8, 9.6) | 0.001 |
TyG-BMI index | 271.6 (239.3, 321.1) | 277.7 (242.0, 320.4) | 0.344 |
TyG-WHtR index | 5.5 (4.9, 6.2) | 5.8 (5.3, 6.5) | < 0.001 |
TyG-WWI index | 98.9 (91.0, 107.3) | 105.4 (98.6, 112.2) | < 0.001 |
TyG-WC index | 929.1 (821.6, 1039.0) | 972.1 (879.6, 1083.8) | < 0.001 |
Overweight or obesity, n (%) | 895 (88.2) | 1082 (92.5) | 0.029 |
Hypertriglyceridemia, n (%) | 505 (56.5) | 720 (64.3) | 0.027 |
High blood pressure, n (%) | 436 (42.8) | 858 (69.9) | < 0.001 |
Low HDL-C, n (%) | 554 (57.8) | 657 (60.1) | 0.580 |
diabetes, n(%) | 299 (26.3) | 597 (44.0) | < 0.001 |
Heart attack, n (%) | 19 (1.7) | 118 (10.9) | < 0.001 |
Antihypertensive medications, n (%) | 146 (15.8) | 415 (34.0) | < 0.001 |
Lipid-lowering medications, n (%) | 32 (4.4) | 84 (8.3) | 0.020 |
Glucose-lowering medications, n (%) | 57 (4.6) | 165 (12.8) | < 0.001 |