The association between stress-induced hyperglycemia ratio and cardiovascular events as well as all-cause mortality in patients with chronic kidney disease and diabetic nephropathy

Table 4 Threshold effect analysis of the SHR on all-cause and cardiovascular mortality in patients with CKD combined with diabetes

Mortality risk	Mortality	Adjusted HR (95%CI)	P-value
All-cause mortality
Total	722
Fitting by two-piecewise Cox proportional risk model inflection point		0.971
SHR ≤0.971	332	0.17(0.06, 0.47)	P<0.001
SHR>0.971	390	1.99(1.30, 3.06)	P=0.002
Cardiovascular mortality
Total	222
Fitting by two-piecewise Cox proportional risk model inflection point		1.059
SHR ≤1.059	152	0.06(0.02, 0.27)	P<0.001
SHR>1.059	70	5.02(1.21, 20.8)”	P=0.026

Multiple Cox regression model: Model 1: Adjusted for Age, Sex, Race; Model 2: Adjusted for Age, Sex, Race, Education, Marital, Serum Cotinine, Body mass index, Smoking status; Model 3: Adjusted for Age, gender, Race, Education, Marital, Serum Cotinine, Body mass index, Smoking status, Hypertension, Hyperlipidemia, Cardiovascular disease

ISSN: 1475-2840