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Fig. 4 | Cardiovascular Diabetology

Fig. 4

From: Evaluating sex-specific responses to western diet across the lifespan: impact on cardiac function and transcriptomic signatures in C57BL/6J mice at 530 and 640/750 days of age

Fig. 4

Analysis of principal components and UMAP clustering of left ventricular mRNA expression data. A Elbow plot illustrating the variance percentages explained by each principal component. Annotated bars indicate the principal components that exhibit the most significant separation for the specified condition. B–D Uniform manifold approximation and projection (UMAP) clustering of left ventricular mRNA expression data. Each dot represents a sample, with color coding corresponding to sex (B) (male/female; red/green), age (C) (530 and 750/640 days; red/green), and dietary regimen (D) (normal diet (ND)/western diet (WD); red/green)

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Cardiovascular Diabetology

ISSN: 1475-2840