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Fig. 3 | Cardiovascular Diabetology

Fig. 3

From: Probing erythrocytes as sensitive and reliable sensors of metabolic disturbances in the crosstalk between childhood obesity and insulin resistance: findings from an observational study, in vivo challenge tests, and ex vivo incubation assays

Fig. 3

Schematic representation of time-dependent trajectories showing the effect of the oral glucose tolerance test in metabolite levels. (A) Glycolytic intermediates; (B) hippuric acid; (C) ketone bodies; (D) Krebs intermediates; (E) free fatty acids; (F) branched chain amino acids; (G) other amino acids; (H) nucleotide metabolism; (I) phospholipids and sphingolipids; (J) glutathione metabolism; (K) corticosteroids; (L) bile acids. † Denotes significant differences at 60 min when compared to the baseline (in black when differences are found within the ObIR- group, in grey when differences are found within the ObIR + group); ‡ denotes significant differences at 120 min when compared to the baseline (in black when differences are found within the ObIR- group, in grey when differences are found within the ObIR + group); ₸ denotes significant differences at 120 min when compared to 60 min (in black when differences are found within the ObIR- group, in grey when differences are found within the ObIR + group).

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Cardiovascular Diabetology

ISSN: 1475-2840