Fig. 4

Genetic associations between fasting insulin levels and Lp(a) in additional sensitivity analysis. Each genetic variant included in the analysis is represented as a point + 95% CI. Localization on the horizontal axis represents the correlation of the variant with exposure (plasma fasting insulin, inverse variance normal transformed values). Localization on the vertical axis represents the correlation of the variant with the outcome (Lp(a), inverse-rank normalized). Lines represent estimates of different MR methods.