Interdependence between myocardial deformation and perfusion in patients with T2DM and HFpEF: a feature-tracking and stress perfusion CMR study

Table 6 Receiver operating characteristic curve analysis for the detection of HFpEF

	AUC	95%CI	P-value	Cutoff value	Sensitivity	Specificity	PPV	NPV
Total population (n = 206)
Global rest PI	0.735	0.656–0.813	< 0.0001	0.11^*	0.73	0.80	0.67	0.84
Global stress PI	0.848	0.794–0.901	< 0.0001	0.16^*	0.95	0.67	0.61	0.96
Global MPRI, ratio	0.808	0.749–0.867	< 0.0001	1.30^*	0.93	0.72	0.65	0.95
Longitudinal PDSR, s⁻¹	0.591	0.509–0.672	0.0311	1.08^*	0.72	0.53	0.46	0.77
Circumferential PDSR, s⁻¹	0.722	0.646–0.799	< 0.0001	0.78^*	0.51	0.92	0.78	0.77
LA reservoir, %	0.752	0.683–0.822	< 0.0001	42.77^*	0.76	0.80	0.67	0.85
LA conduit, %	0.595	0.511–0.678	0.0245	30.94^*	0.91	0.36	0.44	0.87
LA booster, %	0.857	0.804–0.910	< 0.0001	16.70^*	0.91	0.79	0.71	0.94
T2DM population (n = 156)
Mean E/e′, ratio	0.897	0.841–0.954	< 0.0001	15	0.76	0.94	0.91	0.83
LAVI, mL/m²	0.690	0.609–0.773	< 0.0001	34	0.46	0.90	0.79	0.67
Global rest PI	0.740	0.650–0.831	< 0.0001	0.11^*	0.73	0.85	0.80	0.80
Global stress PI	0.803	0.732–0.874	< 0.0001	0.14^*	0.70	0.88	0.82	0.78
Global MPRI, ratio	0.740	0.661–0.819	< 0.0001	1.30^*	0.93	0.60	0.65	0.92
Radial PSSR, s⁻¹	0.651	0.555–0.747	0.0012	1.90^*	0.97	0.59	0.66	0.97
Circumferential PDSR, s⁻¹	0.700	0.616–0.784	< 0.0001	0.78^*	0.51	0.90	0.81	0.70
LA reservoir, %	0.679	0.590–0.768	< 0.0001	42.77^*	0.76	0.71	0.68	0.78
LA booster, %	0.790	0.717–0.864	< 0.0001	16.70^*	0.91	0.68	0.70	0.90

PI perfusion index, MPRI myocardial perfusion reserve index, PDSR peak diastolic strain rate, LA left atrial, E/e′, early filling velocity on transmitral Doppler/early relaxation velocity on tissue Doppler, LAVI left atrial volume index, PSSR peak systolic strain rate;
^*Optimal cutoff value

ISSN: 1475-2840