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Table 5 Mediating effects of T2DM on LA reservoir strain and LA booster strain with mediators of LV circumferential PDSR and global MPRI

From: Interdependence between myocardial deformation and perfusion in patients with T2DM and HFpEF: a feature-tracking and stress perfusion CMR study

 

LA reservoir strain

LA booster strain

Direct effect

Indirect effect

Direct effect

Indirect effect

LV circumferential PDSR, s−1

0.236 (-0.710, 1.182)

0.067 (-0.210, 0.356)

-0.286 (-0.808, 0.236)

-0.082 (-0.249, 0.046)

global MPRI, ratio

3.248(1.515, 4.981)*

0.276 (0.105, 0.528)*

-3.412 (-4.368, -2.456)*

-0.290 (-0.523, -0.121) *

  1. LA left atrial, LV left ventricular, PDSR peak diastolic strain rate, MPRI myocardial perfusion reserve index
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Cardiovascular Diabetology

ISSN: 1475-2840