Interdependence between myocardial deformation and perfusion in patients with T2DM and HFpEF: a feature-tracking and stress perfusion CMR study

Table 2 CMR findings in 3 groups

	Control n = 50	T2DM–non-HFpEF n = 82	T2DM–HFpEF n = 74	P-value
CMR–LV strain
Torsion, º/cm	1.36 (1.32, 1.73)	1.52 (1.48, 1.97)^*	1.54 (1.52, 1.62)^*	< 0.001^#
PSSR, s⁻¹
Longitudinal	-1.05 ± 0.23	-1.03 ± 0.12	-0.98 ± 0.22	0.089
Circumferential	-1.00 ± 0.05	-1.00 ± 0.08	-1.00 ± 0.14	0.995
Radial	1.81 ± 0.07	1.87 ± 0.19^*	1.79 ± 0.11^&	< 0.001^#
PDSR, s⁻¹
Longitudinal	1.34 ± 0.32	1.04 ± 0.11^*	1.04 ± 0.21^*	< 0.001^#
Circumferential	1.13 ± 0.27	1.06 ± 0.46	0.73 ± 0.52^*&	< 0.001^#
Radial	-2.12 ± 1.13	-2.18 ± 1.19	-2.12 ± 0.70	0.937
CMR–LA strain
Reservoir, %	44.88 ± 2.57	43.45 ± 3.68^*	41.93 ± 2.75^*&	< 0.001^#
Conduit, %	31.39 ± 2.53	28.98 ± 1.60^*	28.69 ± 3.22^*	< 0.001^#
Booster, %	14.65 ± 1.24	16.34 ± 1.48^*	17.99 ± 1.74^*&	< 0.001^#
CMR–perfusion
Global rest PI	0.14 ± 0.05	0.12 ± 0.02^*	0.11 ± 0.03^*&	< 0.001^#
Global stress PI	0.24 ± 0.08	0.16 ± 0.02^*	0.13 ± 0.02^*&	< 0.001^#
Global MPRI, ratio	1.71 ± 0.26	1.28 ± 0.10^*	1.20 ± 0.11^*&	< 0.001^#

Values are presented as the mean ± SD or median (IQR)
HFpEF Heart failure with preserved ejection fraction, LVEF left ventricular ejection fraction, PI perfusion index, MPRI myocardial perfusion reserve index, PSSR peak systolic strain rate, PDSR peak diastolic strain rate
^*p < 0.05 vs. control group; ^&p < 0.05 vs. T2DM–non-HFpEF group; ^#p < 0.001

ISSN: 1475-2840