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Table 4 Associations of cumulative TyG-BMI (Q1-Q4) with FI trajectory and frail incidence

From: Relationship between changes in the triglyceride glucose-body mass index and frail development trajectory and incidence in middle-aged and elderly individuals: a national cohort study

Variables

Events/n

Model 1a

 

Model 2b

 

Cumulative TyG-BMIc

(N = 9135)

Trajectory 2e

OR (95% CI)

P

OR (95% CI)

P

Q1 (339.22, 536.62)

926/2284

Reference

 

Reference

 

Q2 (536.65, 609.20)

906/2283

0.95 (0.84, 1.07)

0.361

1.04 (0.92, 1.19)

0.506

Q3 (609.25, 694.32)

944/2285

1.07 (0.95, 1.2)

0.304

1.20 (1.05, 1.36)

0.007

Q4 (694.40, 1079.53)

1164/2283

1.67 (1.48, 1.88)

< 0.001

1.94 (1.70, 2.22)

< 0.001

 

P for trendf

 

< 0.001

P for trendf

< 0.001

Cumulative TyG-BMIc

(N = 8185)

Fraild

HR (95% CI)

 

HR (95% CI)

 

Q1 (339.22, 536.62)

690/2048

Reference

 

Reference

 

Q2 (536.65, 609.20)

695/2072

0.97 (0.88, 1.06)

0.450

1.04 (0.95, 1.14)

0.383

Q3 (609.25, 694.32)

727/2068

1.02 (0.93, 1.11)

0.711

1.10 (1.00, 1.21)

0.043

Q4 (694.40, 1079.53)

878/1997

1.33 (1.22, 1.45)

< 0.001

1.46 (1.33, 1.60)

< 0.001

 

P for trendf

 

< 0.001

P for trendf

< 0.001

  1. a Unadjusted for covariates; b Adjusted for Age, gender, marital status, smoke, drink, educational level, physical activity, CRP, HbA1c; Q1-4 Quartile 1–4; c The cumulative TyG-BMI was calculated by the formula (r1TyG-BMI + r3TyG-BMI)/2× time(r3 − r1) and then it was split into quartiles; c Frailty index ≥ 0.25; e Trajectory 2 of FI; f Tests for linear trends were performed by modelling the median value of each quantile to test ordered relations across quantiles of the TyG-BMI