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Fig. 2 | Cardiovascular Diabetology

Fig. 2

From: Empagliflozin protects against heart failure with preserved ejection fraction partly by inhibiting the senescence-associated STAT1–STING axis

Fig. 2

Effects of EMPA on the protein expression profile of HFpEF mice. 4D-DIA quantitative proteomics analysis was performed at the heart tissue level in control, HFpEF and EMPA-treated mice. A The number of DEPs that were upregulated, downregulated and in total; B Venn diagram of DEPs for the three groups; C Heatmap of coregulated proteins in all groups; D K-means clusters containing ten subclasses; E Gene Ontology (GO) enrichment and interaction network analysis based on DEPs in cluster 10

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Cardiovascular Diabetology

ISSN: 1475-2840