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Table 1 Baseline characteristics of female and male patients with T2D of the study population

From: Sex differences in the diagnostic algorithm of screening for heart failure by symptoms and NT-proBNP in patients with type 2 diabetes

 

All

Men

Women

p-value

N (%)

2083

1148 (55.1%)

935 (44.9%)

 

Age (years)

60.92 (± 0.29)

60.29 (± 0.37)

61.68 (± 0.44)

0.009

BMI (kg/m²)

29.19 (± 0.13)

28.9 (± 0.16)

29.55 (± 0.19)

0.007

HbA1c (%)

7.37* (± 0.03)

7.26* (± 0.04)

7.48 (± 0.04)

< 0.001

NT-proBNP (pg/ml)

244.75 (± 8.88)

248.29 (± 13.08)

240.41 (± 11.54)

< 0.001

Creatinine (mg/dl)

1.04 (± 0.01)

1.12 (± 0.01)

0.94 (± 0.01)

< 0.001

eGFR (ml/min)

73.27 (± 0.1)

76.78 (± 0.56)

68.94 (± 0.57)

< 0.001

DM duration (years)

13.64 (± 0.27)

13.43 (± 0.37)

13.89 (± 0.4)

0.346

LDL (mg/dl)

104.63 (± 0.78)

103.84 (± 1.15)

105.60 (± 1.02)

0.029

Arterial Hypertension (%)

1437 (69.0%)

784 (65.2%)

653 (69.8%)

0.448

AF (%)

52 (2.5%)

32 (2,8%)

20 (2.1%)

0.340

CABG (%)

74 (3.6%)

63 (5.5%)

11 (1.2%)

< 0.001

PCI (%)

74 (3.6%)

53 (4.6%)

21 (2.2%)

0.014

NYHA class

   

< 0.001

 NYHA I (%)

1782 (85.5%)

1015 (88.4%)

767 (82.0%)

 

 NYHA II (%)

234 (11.2%)

107 (9.3%)

127 (13.6%)

 

 NYHA III (%)

63 (3.0%)

26 (2.3%)

37 (4.0%)

 

 NYHA IV (%)

4 (0.2%)

0

4 (0.4%)

 

RAS inhibitors (%)

1212 (58.2%)**

669 (58.3%)

543 (58.1%)

0.958

Beta-blocker (%)

599*** (28.9%)

329 (28.7%)

270 (29.1%)

0.847

Diuretics (%)

695**** (33.4%)

357 (31.1%)

338 (36.3%)

0.014

Aldosterone antagonist (%)

65***** (3.1%)

30 (2.6%)

35 (3.8%)

0.220

Insulin (%)

1138 (54.6%)

640 (55.8%)

498 (53.3%)

0.257

Statin (%)

918 (44.1%)

496 (43.2%)

422 (45.1%)

0.656

PAD (%)

189 (9.1%)

94 (8.2%)

95 (10.2%)

0.119

CVD (%)

111 (0.5%)

74 (6.4%)

37 (4.0%)

0.012

  1. Data is presented as mean ± standard error or percentages
  2. BMI: body mass index, HbA1c: glycated haemoglobin, eGFR: estimated glomerular filtration rate, DM: Diabetes mellitus, LDL: low-density lipoprotein, AF: atrial fibrillation, CABG: coronary artery bypass graft, PCI: percutaneous coronary intervention, NYHA: New York Heart Association, RAS: renin-angiotensin system, PAD: Peripheral artery occlusive disease, CVD: Cerebrovascular disease
  3. *Missing data from 19 patients
  4. **Missing data from 5 patients
  5. ***Missing data from 9 patients
  6. ****Missing data from 5 patients
  7. *****Missing data from 15 patients