Figure 3

Beneficial effects of AC3174 on fasting glycemic control after 4 weeks of treatment. (A) Fasting serum glucose concentrations. No significant differences among groups. (B) Fasting serum insulin concentrations. P = 0.0020 for one-way ANOVA. The pooled-over-time means of the low salt, AC3174, and captopril groups were significantly different from the high salt group (P ≤ 0.05). (C) HOMA. P = 0.0014 for one-way ANOVA. The pooled-over-time means for all treatment groups except GLP-1 were significantly different from the high salt group (P ≤ 0.05).